Cagrilintide is lipidated long-acting analogue of amylin (islet amyloid polypeptide) (formula C194H312N54O59S2, average mass 4,409 g/mol, CAS 1415456-99-3). Cagrilintide is sold here for laboratory research in 3 sizes (2mg to 10mg), from $60.00 a vial. It is not an FDA-approved medicine. Research use only, and never for people or animals.
Cagrilintide specifications
| Product name | Cagrilintide |
|---|---|
| Formula | C194H312N54O59S2 |
| Average mass | 4,409 g/mol |
| CAS number | 1415456-99-3 |
| Physical form | Freeze-dried powder, a solid cake in a sealed vial |
| Appearance | White to off-white cake |
| Sizes on this page | 2mg · 5mg · 10mg |
| Purity specification | ≥99% by RP-HPLC. The number for the lot you receive is whatever its own certificate says. |
| Identity check | Mass spectrometry, read against the mass this compound should have |
| Net content | Weighed per lot and reported separately from purity |
| Lot documentation | Tested by Kovera Labs; each lot's certificate posts here when it is reported |
| Storage | Sealed, cold and out of the light |
| Ships from | Santa Ana, California by USPS with tracking on every order, same business day on verified in-stock orders placed before 12 PM Pacific |
| Intended use | Laboratory research only. Not for human or animal use. |
What is Cagrilintide, and what is it used for?
Supplier lists write it as Cagrilintide peptides or peptide Cagrilintide; every one of those is this record, and the lot certificate further down counts for more than the wording on a label.
Chemically: molecular formula C194H312N54O59S2, average mass 4409 g/mol (PubChem CID 171397054). Those figures are what the identity test on a certificate is read against.
Lipidated long-acting analogue of amylin (islet amyloid polypeptide).
A non-selective agonist at calcitonin family G-protein-coupled receptors — it activates both the amylin receptors, which are heterodimers of the calcitonin receptor with receptor activity-modifying proteins, and the calcitonin receptor itself. Compounds with this profile are termed dual amylin and calcitonin receptor agonists.
Receptor pharmacology across calcitonin-family receptors, and preclinical metabolic models in high-fat-diet and diabetic rats. Investigational; developed by Novo Nordisk.
No approved product. The relative contribution of amylin-receptor versus calcitonin-receptor activation to any observed effect is an open question the field is actively arguing about.
Cagrilintide for sale: 2mg, 5mg and 10mg vials, price per mg
Cagrilintide is sold in 3 sizes here, 2mg, 5mg and 10mg, from $60.00 a vial. Every way of buying is in the table; the per-mg figure under each price is the one that compares across sizes.
Volume and subscription pricing by size
| Size | One vial | 10–19 vials−10% | 20 vials−15% | Subscribe monthly−6% from shipment 2 | Availability |
|---|---|---|---|---|---|
| Cagrilintide 2mg | $60.00$30.00/mg | $54.00a vial · $27.00/mg | $51.00a vial · $25.50/mg | $56.40a vial, shipment 2 on · $28.20/mg | Backordered — waitlist |
| Cagrilintide 5mg | $75.00$15.00/mg | $67.50a vial · $13.50/mg | $63.75a vial · $12.75/mg | $70.50a vial, shipment 2 on · $14.10/mg | Backordered — waitlist |
| Cagrilintide 10mg | $85.00$8.50/mg | $76.50a vial · $7.65/mg | $72.25a vial · $7.22/mg | $79.90a vial, shipment 2 on · $7.99/mg | Backordered — waitlist |
Volume tiers are per size and do not combine across sizes (see bulk pricing). Subscribe & Save takes 6% every month, 4% every 2 months or 2% every 3 months off from shipment 2, two shipments minimum, and stacks on the volume tier: the lowest this record ever bills is $23.97 per mg, twenty 2mg vials on a monthly subscription from shipment 2 onward.
Nothing is added at checkout except the USPS shipping you choose; dispatch and delivery are the same on every order. The cost-per-milligram tool ranks the whole catalog by price per mg.
Where to buy Cagrilintide: what to check before you order from anyone
Before ordering Cagrilintide from anyone, us included, run the 5 checks on verifying a certificate; the first is that the report resolves on the laboratory's own site, and a seller who cannot pass them is asking for the trust a certificate exists to replace.
Cagrilintide vs Retatrutide and Tirzepatide: different molecules, separate records
Cagrilintide vs Retatrutide, or Retatrutide vs Cagrilintide, is the comparison people search most, with Tirzepatide close behind, and they are not the same thing. Each is a different molecule with a different formula, mass and research record, and each has its own certificate here. Retatrutide cagrilintide blend is searched too; no such blend is sold here, each is its own record with its own certificate, and a certificate for a blend from anyone else reports on the mixture, not on either compound alone.
Retatrutide vs Cagrilintide: the same comparison, side by side
| Record | Class | Formula | Avg. mass | Sizes here |
|---|---|---|---|---|
| Cagrilintide | Lipidated long-acting analogue of amylin (islet amyloid polypeptide). | C194H312N54O59S2 | 4409 | 2mg · 5mg · 10mg from $60.00 |
| Retatrutide | An experimental peptide that works on three incretin receptors at once. | C221H342N46O68 | 4731.3 | 5mg · 10mg · 15mg · 20mg · 30mg · 40mg · 50mg · 60mg from $80.00 |
| Tirzepatide | A peptide that works on the GIP and GLP-1 receptors at the same time. | C225H348N48O68 | 4813 | 5mg · 10mg · 15mg · 20mg · 30mg · 40mg · 50mg · 60mg · 70mg · 80mg · 90mg · 100mg · 110mg · 120mg from $50.00 |
Documentation compared in full: Cagrilintide vs Retatrutide, side by side · Cagrilintide vs Tirzepatide, side by side.
Cagrilintide guides and documentation
Written to answer the questions that come up around Cagrilintide specifically, what its paperwork should show, how it is handled, and how to judge a supplier selling it.
- Cagrilintide certificate of analysis: what each field actually proves
- Cagrilintide identity testing, and why a mass number alone is not proof
- Cagrilintide Storage and Stability in the Laboratory
- CagriSema Identity Testing: How It Is Confirmed
- CagriSema Storage and Stability in the Laboratory
The full library, grouped by what you came to answer, is in the laboratory guides.
The Cagrilintide certificate: lot, purity, identity, and how to verify it
A certificate answers identity, purity and net content as three separate questions, each with the method that produced it and the date it was run, how to read one covers what each field does and does not cover. For Cagrilintide that means a mass spectrum landing on 4,409 g/mol for C194H312N54O59S2, the figure published against PubChem CID 171397054.
Listings elsewhere describe Cagrilintide as an acetate, an arginate salt or an N-acetyl form. Those are different chemical forms with different masses, and a certificate identifies which one was actually tested. The form of the lot on this page is whatever its certificate states; it is not assumed from a listing name, ours included.
Cagrilintide certificates post here and in the certificate index when Kovera Labs reports on the lot.
Solution arithmetic for the bench, with no administration guidance: the vial concentration calculator, preset to Cagrilintide.
Where the FDA stands on Cagrilintide
FDA status, and what this listing is Not an FDA-approved drug product
The FDA has not approved this compound for anything, and nothing in this catalog is a medicine.
Status verified 2026-08-25. Check the primary source before relying on this summary.
It is sold as laboratory material under the research-use restriction below. Being listed is not an approval, and not a claim that it is safe, effective or right for any purpose.
Cagrilintide research: what the published studies examine
Status: No FDA-approved application. This compound is sold as laboratory material. Where research on it has been published, it sits at the animal, cell or early-human stage, and this record does not summarize what it found. A supplier is not a neutral judge of evidence about its own catalog.
Cagrilintide, developed as AM833, is a lipidated amylin analogue, and the interesting thing about its pharmacology is that it is deliberately NOT selective. Amylin receptors are not standalone proteins: they are heterodimers of the calcitonin receptor paired with receptor activity-modifying proteins, so a molecule engaging that family can act at the amylin receptors, at the calcitonin receptor alone, or at both. Cagrilintide does both, which places it in the class termed dual amylin and calcitonin receptor agonists.
The evidence suggests this matters rather than being incidental: selective activation of the calcitonin receptor alone is reported as not efficacious, while non-selective agonists appear to have improved effect, so the balance between the two arms is thought to be part of the mechanism. The lipidation is the standard albumin-binding strategy used across this class to extend circulating time.
| Reported observation | Model | Source |
|---|---|---|
| Pharmacology was profiled across 25 endpoints and compared with amylin-receptor-selective and non-selective lipidated analogues (AM1213, AM1784), the clinically used agonists pramlintide and salmon calcitonin, and prototypical selective agonists human calcitonin and rat amylin. AM833 was shown to have a unique profile across measures of receptor binding, activation and regulation, acting as a non-selective agonist of calcitonin family receptors. | recombinant receptor pharmacology across 25 endpoints, HEK293 and other cell systems | Fletcher and colleagues, AM833 is a novel agonist of calcitonin family G protein-coupled receptors: pharmacological comparison with six selective and nonselective agonists, Journal of Pharmacology and Experimental Therapeutics (2021)Monash University with Novo Nordisk co-authors. The 25-endpoint comparison against seven reference agonists is unusually thorough receptor work. |
| A head-to-head preclinical comparison against KBP-336, a salmon-calcitonin-derived dual agonist, found both peptides activate amylin and calcitonin receptors in vitro and in vivo, with KBP-336 more potent and biased toward the calcitonin receptor. In high-fat-diet obese and diabetic ZDF rats the highest dose of KBP-336 was superior to cagrilintide on body weight, and KBP-336 was superior on glucose control — the authors interpret this as evidence that receptor activation BALANCE, not simply potency, determines the outcome. | receptor-specific assays in vitro and in vivo, high-fat-diet obese rats and ZDF diabetic rats | Larsen and colleagues, Does receptor balance matter? Comparing the efficacies of the dual amylin and calcitonin receptor agonists cagrilintide and KBP-336 on metabolic parameters in preclinical models, Biomedicine and Pharmacotherapy (2022)Authored at Nordic Bioscience and KeyBioscience, who develop the comparator that won. Read the ranking with that in mind; the receptor-balance point stands regardless. |
Open questions. The receptor pharmacology is well characterized and the honest headline is that nobody yet knows which arm of it does the work. Selective calcitonin receptor activation is reported as ineffective, non-selective agonism appears better, and a competing compound with a different balance outperformed cagrilintide in the one published head-to-head — in a paper written by that competitor's developers.
Amylin and calcitonin receptors are also expressed well beyond the tissues of metabolic interest, calcitonin signalling being centrally involved in bone and calcium handling, so a non-selective agonist has effects wherever the family is expressed. Cagrilintide is investigational with no approval anywhere. This page does not reproduce clinical efficacy endpoints.
That is a deliberate and consistent choice across every incretin compound on this catalog: those results describe a supervised therapy given to patients under medical care, which is a different thing from laboratory material, and printing them beside a purchase control would blur that distinction rather than inform anyone. Tolerability findings from the same trials are reported, because how often a compound causes adverse events is a property of the compound.
Finally, the point that applies to every reseller including this one: a vial bearing one of these names is related to the developed molecule by claimed sequence identity alone, and that claim is exactly what an identity assay on the specific lot exists to test.
Each row above describes an observation in the stated model. None of it describes what Cagrilintide would do in a person or an animal outside that model, and none of it is a recommendation to use it for anything.
How to store Cagrilintide: refrigeration and shelf life
Keep the sealed vial cold and out of the light and it stays as it left the lab. Once it is mixed into a solution, how long it holds up depends on the compound, what it was mixed with, how strong the solution is and how cold it is kept — too many variables for anyone to print one shelf life on a label. So laboratories write the date on whatever they prepare and keep their own record of it.
For solution preparation arithmetic on the bench, concentration, per-graduation values and molarity, use the vial concentration calculator, which opens with the Cagrilintide sizes stocked here already loaded. It covers laboratory measurement only and contains no administration guidance.
