This page compares what is documented about 5-AMINO-1MQ and MOTS-c (Human), rather than ranking them by effect. What each molecule is, the sizes and prices actually carried, what the certificate covers, and how the two differ on the bench. Everything here is research-use-only material and we do not publish outcome, dosing or administration content for any compound in the catalogue.
What is 5-AMINO-1MQ and what is MOTS-c (Human)?
5-AMINO-1MQ. 5-amino-1MQ is a small-molecule NNMT inhibitor from the UT Southwestern programme, studied in cellular-metabolism models where the NNMT pathway intersects NAD+ salvage.
MOTS-c (Human). MOTS-c is encoded inside the mitochondrial 12S rRNA gene — a mitochondrial-derived peptide studied in metabolic-signalling and exercise-biology models since 2015.
How do 5-AMINO-1MQ and MOTS-c (Human) compare on price and size?
| 5-AMINO-1MQ | MOTS-c (Human) | |
|---|---|---|
| Sizes carried | 5 mg, 50 mg | 10 mg, 20 mg, 40 mg |
| From | $55.00 | $60.00 |
| Best price per unit | $1.80 / mg | $2.50 / mg |
| Availability | Backordered — waitlist | Backordered — waitlist |
| Certificate | Lot certificate on the product page | Lot certificate on the product page |
| Molecular formula | C10H11N2+ | C101H152N28O22S2 |
| Molar mass | 159.21 g/mol | 2,174.6 g/mol |
| Source | PubChem CID 950107 | PubChem CID 146675088 |
| Research area | NNMT-pathway research | mitochondrial-signalling research |
At their best sizes 5-AMINO-1MQ works out at $1.80 per mg against $2.50 for MOTS-c (Human) — 39% more for the mg. Vial prices start at $55.00 and $60.00 respectively, which is the number most people compare and the one that says least, because the two are not sold in the same sizes. Full sizes, tier pricing and the lot certificate sit on the 5-AMINO-1MQ page and the MOTS-c (Human) page.
What is each one studied for?
What the published literature investigates, which is a different question from what either will do, and the only one of the two a supplier can answer.
5-AMINO-1MQ is studied in nnmt-pathway research. NNMT-pathway research is young and growing, and 5-amino-1MQ remains its most-used inhibitor probe.
MOTS-c (Human) is studied in mitochondrial-signalling research. Mitochondrial-derived peptides are a young and fast-moving corner of metabolic research, with MOTS-c the most-studied of the family.
Studied in the same area does not make two compounds interchangeable, and the research library holds the per-compound documentation.
Mots C vs 5 AMINO 1MQ: how they differ on the bench
MOTS-c (Human). MOTS-c is a 16-residue peptide with a critical central motif; sequence-level identity confirmation matters more here than for longer, more forgiving chains.
5-AMINO-1MQ. Not a peptide at all — a quinolinium small molecule, which is why its identity testing runs different methods than the rest of the catalog.
On naming, because the two are written several ways and the difference is not always obvious: 5-AMINO-1MQ is also written 5 amino 1mq; MOTS-c (Human) is also written mots c. They refer to the same materials described here, and the certificate for a lot uses the name on this page. The comparison itself is usually typed 5 AMINO 1MQ vs Mots C.
What actually differs between MOTS-c (Human) and 5-AMINO-1MQ
Worth doing the arithmetic before comparing sizes: MOTS-c (Human) is 2,174.6 g/mol and 5-AMINO-1MQ is 159.21 g/mol, a factor of 13.7. A milligram of 5-AMINO-1MQ therefore contains roughly 13.7 times as many molecules as a milligram of MOTS-c (Human), so two vials of the same labelled mass hold quite different amounts of substance. Equal milligrams are not equal moles, which is what the molarity calculator exists to convert, and it is the reason a price-per-milligram comparison and a price-per-mole comparison can point at different vials.
Identity is the other analytical axis, and it is settled per lot rather than per compound. 5-AMINO-1MQ. The figures above are for the cation alone. The material is supplied as a salt of that cation, and the counter-ion is named on the lot certificate. MOTS-c (Human). Catalogued as MOTS-c, and the certificate's identity test resolves to that.
Both are released against a certificate reporting identity, purity by the stated method and net peptide content, readable before anything is bought.
Which is better, Mots C or 5 AMINO 1MQ?
Neither Mots C nor 5 AMINO 1MQ is ranked against the other here, and the refusal is deliberate. Better, safer and stronger are questions about effects in a living system, and we sell neither compound for use in one — why none of these pages ranks two compounds sets out the reasoning in full.
What it does instead, for these two:
- 5-AMINO-1MQ is the cheaper of the two per mg, at $1.80 against $2.50.
- MOTS-c (Human) is the heavier molecule by a factor of 13.7, so equal milligrams are not equal moles.
- 5-AMINO-1MQ is carried in 2 sizes and MOTS-c (Human) in 3, and each lot carries its own certificate.
Every one of those is checkable before you buy.
Common questions
What is the difference between MOTS-c (Human) and 5-AMINO-1MQ?
Different molecules before anything else: MOTS-c (Human) is C101H152N28O22S2 and 5-AMINO-1MQ is C10H11N2+. MOTS-c is encoded inside the mitochondrial 12S rRNA gene — a mitochondrial-derived peptide studied in metabolic-signalling and exercise-biology models since 2015. 5-amino-1MQ is a small-molecule NNMT inhibitor from the UT Southwestern programme, studied in cellular-metabolism models where the NNMT pathway intersects NAD+ salvage.
Which one should I choose?
5-AMINO-1MQ is carried in 5 mg, 50 mg and MOTS-c (Human) in 10 mg, 20 mg, 40 mg, each lot with its own certificate. Which of those suits the work is yours to decide; everything here is research-use-only rather than guidance for use in a human or an animal.
Do both 5-AMINO-1MQ and MOTS-c (Human) come with a certificate of analysis?
Neither is in stock at the moment, so in each case the certificate is the one attached to the lot that arrives. A certificate belongs to a lot, not to a product. It is linked from the product page, and reports identity, purity by the stated method, and net peptide content for the material actually in that lot.
Which is cheaper, MOTS-c (Human) or 5-AMINO-1MQ?
Per mg, 5-AMINO-1MQ at $1.80 against $2.50, taking each one's best size. By vial they start at $55.00 for 5-AMINO-1MQ and $60.00 for MOTS-c (Human), which is the comparison most people make and the one that says least, because the two are not sold in the same sizes.
Is a milligram of 5-AMINO-1MQ the same as a milligram of MOTS-c (Human)?
By mass yes, by amount of substance no. MOTS-c (Human) is 2,174.6 g/mol and 5-AMINO-1MQ is 159.21 g/mol, a factor of 13.7, so a milligram of 5-AMINO-1MQ holds roughly 13.7 times as many molecules. Two vials with the same number on the label are not the same amount of substance, which is what the molarity calculator converts.
FOR LABORATORY AND IN-VITRO RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR PERSONAL, MEDICAL, DIAGNOSTIC, THERAPEUTIC, OR RECREATIONAL USE.