This page compares what is documented about AOD9604 and Semaglutide, rather than ranking them by effect. What each molecule is, the sizes and prices actually carried, what the certificate covers, and how the two differ on the bench. Everything here is research-use-only material and we do not publish outcome, dosing or administration content for any compound in the catalogue.
What is AOD9604 and what is Semaglutide?
AOD9604. AOD9604 is the C-terminal hGH(177-191) fragment with a disulfide loop — studied in lipolysis models precisely because it strips away the rest of the hormone's activity.
Semaglutide. Semaglutide is the most-cited GLP-1 receptor agonist in the research literature, which makes verified reference material a staple for comparative receptor work.
How do AOD9604 and Semaglutide compare on price and size?
| AOD9604 | Semaglutide | |
|---|---|---|
| Sizes carried | 5 mg, 10 mg | 5 mg, 10 mg, 15 mg, 20 mg, 30 mg |
| From | $44.00 | $80.00 |
| Best price per unit | $7.50 / mg | $3.83 / mg |
| Availability | Backordered — waitlist | Backordered — waitlist |
| Certificate | Lot certificate on the product page | Lot certificate on the product page |
| Molecular formula | C78H123N23O23S2 | C187H291N45O59 |
| Molar mass | 1,815.1 g/mol | 4,114 g/mol |
| Source | PubChem CID 71300630 | PubChem CID 56843331 |
| Research area | lipolysis-model research | GLP-1 receptor research |
At their best sizes Semaglutide works out at $3.83 per mg against $7.50 for AOD9604 — 96% more for the mg. Vial prices start at $44.00 and $80.00 respectively, which is the number most people compare and the one that says least, because the two are not sold in the same sizes. Full sizes, tier pricing and the lot certificate sit on the AOD9604 page and the Semaglutide page.
What is each one studied for?
What the published literature investigates, which is a different question from what either will do, and the only one of the two a supplier can answer.
AOD9604 is studied in lipolysis-model research. Fragment-based hormone research continues to use AOD9604 as the canonical example of isolating one activity from a parent hormone.
Semaglutide is studied in glp-1 receptor research. GLP-1 receptor biology continues to dominate metabolic-research publishing, and semaglutide remains its most-cited reference compound.
Studied in the same area does not make two compounds interchangeable, and the research library holds the per-compound documentation.
Semaglutide vs AOD 9604: how they differ on the bench
Semaglutide. Semaglutide degrades along predictable routes — our stability guide maps which storage regime suits sealed powder versus a working solution.
AOD9604. The disulfide bridge is the fragile part: reducing conditions break AOD9604 into something else entirely. Storage dry and dark protects it.
On naming, because the two are written several ways and the difference is not always obvious: AOD9604 is also written aod 9604. They refer to the same materials described here, and the certificate for a lot uses the name on this page. The comparison itself is usually typed AOD 9604 vs Semaglutide.
What actually differs between Semaglutide and AOD9604
Worth doing the arithmetic before comparing sizes: Semaglutide is 4,114 g/mol and AOD9604 is 1,815.1 g/mol, a factor of 2.3. A milligram of AOD9604 therefore contains roughly 2.3 times as many molecules as a milligram of Semaglutide, so two vials of the same labelled mass hold quite different amounts of substance. Equal milligrams are not equal moles, which is what the molarity calculator exists to convert, and it is the reason a price-per-milligram comparison and a price-per-mole comparison can point at different vials.
Identity is the other analytical axis, and it is settled per lot rather than per compound. AOD9604. Catalogued as AOD-9604, and the certificate's identity test resolves to that. Semaglutide. Catalogued as Semaglutide, and the certificate's identity test resolves to that.
Both are released against a certificate reporting identity, purity by the stated method and net peptide content, readable before anything is bought.
Which is better, Semaglutide or AOD 9604?
Neither Semaglutide nor AOD 9604 is ranked against the other here, and the refusal is deliberate. Better, safer and stronger are questions about effects in a living system, and we sell neither compound for use in one — why none of these pages ranks two compounds sets out the reasoning in full.
What it does instead, for these two:
- Semaglutide is the cheaper of the two per mg, at $3.83 against $7.50.
- Semaglutide is the heavier molecule by a factor of 2.3, so equal milligrams are not equal moles.
- AOD9604 is carried in 2 sizes and Semaglutide in 5, and each lot carries its own certificate.
Every one of those is checkable before you buy.
Common questions
What is the difference between Semaglutide and AOD9604?
Different molecules before anything else: Semaglutide is C187H291N45O59 and AOD9604 is C78H123N23O23S2. Semaglutide is the most-cited GLP-1 receptor agonist in the research literature, which makes verified reference material a staple for comparative receptor work. AOD9604 is the C-terminal hGH(177-191) fragment with a disulfide loop — studied in lipolysis models precisely because it strips away the rest of the hormone's activity.
Which one should I choose?
AOD9604 is carried in 5 mg, 10 mg and Semaglutide in 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, each lot with its own certificate. Which of those suits the work is yours to decide; everything here is research-use-only rather than guidance for use in a human or an animal.
Do both AOD9604 and Semaglutide come with a certificate of analysis?
Neither is in stock at the moment, so in each case the certificate is the one attached to the lot that arrives. A certificate belongs to a lot, not to a product. It is linked from the product page, and reports identity, purity by the stated method, and net peptide content for the material actually in that lot.
Which is cheaper, Semaglutide or AOD9604?
Per mg, Semaglutide at $3.83 against $7.50, taking each one's best size. By vial they start at $44.00 for AOD9604 and $80.00 for Semaglutide, which is the comparison most people make and the one that says least, because the two are not sold in the same sizes.
Is a milligram of AOD9604 the same as a milligram of Semaglutide?
By mass yes, by amount of substance no. Semaglutide is 4,114 g/mol and AOD9604 is 1,815.1 g/mol, a factor of 2.3, so a milligram of AOD9604 holds roughly 2.3 times as many molecules. Two vials with the same number on the label are not the same amount of substance, which is what the molarity calculator converts.
FOR LABORATORY AND IN-VITRO RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR PERSONAL, MEDICAL, DIAGNOSTIC, THERAPEUTIC, OR RECREATIONAL USE.