Thymosin Alpha 1 is a 28-residue acetylated peptide originally isolated from thymic tissue; the pharmaceutical form is called thymalfasin (formula C129H215N33O55, average mass 3,108.3 g/mol, CAS 62304-98-7). Thymosin Alpha-1 is sold here for laboratory research in 2 sizes (5mg to 10mg), from $70.00 a vial. It is not an FDA-approved medicine. Research use only, and never for people or animals.
Thymosin Alpha 1 specifications
| Product name | Thymosin Alpha-1 |
|---|---|
| Also sold as | thymalfasin, Thymosin alpha 1 peptide |
| Formula | C129H215N33O55 |
| Average mass | 3,108.3 g/mol |
| CAS number | 62304-98-7 |
| Physical form | Freeze-dried powder, a solid cake in a sealed vial |
| Appearance | White to off-white cake |
| Sizes on this page | 5mg · 10mg |
| Purity specification | ≥99% by RP-HPLC. The number for the lot you receive is whatever its own certificate says. |
| Identity check | Mass spectrometry, read against the mass this compound should have |
| Net content | Weighed per lot and reported separately from purity |
| Lot documentation | Lot numbers assigned for 2 of 2 sizes; each lot's certificate posts here when Kovera Labs reports it |
| Storage | Sealed, cold and out of the light |
| Ships from | Santa Ana, California by USPS with tracking on every order, same business day on verified in-stock orders placed before 12 PM Pacific |
| Intended use | Laboratory research only. Not for human or animal use. |
What is Thymosin Alpha 1, and what is it used for?
Thymosin Alpha 1 is also listed and searched as thymalfasin, Thymosin alpha 1 peptide. They all mean the same compound. Supplier lists write it as Thymosin Alpha 1 peptides or peptide Thymosin Alpha 1 as well; every one of those is this record. A name is not a test, which is why the lot record further down counts for more than the wording on a label.
Chemically: molecular formula C129H215N33O55, average mass 3108.3 g/mol (PubChem CID 16130571). Those figures are what the identity test on a certificate is read against.
A 28-residue acetylated peptide originally isolated from thymic tissue; the pharmaceutical form is called thymalfasin.
Acts through Toll-like receptors on myeloid and plasmacytoid dendritic cells, initiating signalling that leads to production of immune-related cytokines. The mechanism is described as pleiotropic — it affects multiple immune cell subsets rather than acting on a single target.
Immune suppression associated with infection, cancer and ageing, and as a vaccine adjuvant. Registered and used in a number of countries; not approved in the United States.
No United States approval. Effects on immune cell subsets are better established than effects on clinical outcomes.
Thymosin Alpha 1 for sale: 5mg and 10mg vials, price per mg
Thymosin Alpha 1 is sold in 2 sizes here, 5mg and 10mg, from $70.00 a vial. Thymosin Alpha 1 cost and Thymosin Alpha 1 price per mg by size are in the table, at each volume tier and on subscription; the per-mg figure under each price is the one that compares across sizes.
Volume and subscription pricing by size
| Size | One vial | 10–19 vials−10% | 20 vials−15% | Subscribe monthly−6% from shipment 2 | Availability |
|---|---|---|---|---|---|
| Thymosin Alpha 1 5mg | $70.00$14.00/mg | $63.00a vial · $12.60/mg | $59.50a vial · $11.90/mg | $65.80a vial, shipment 2 on · $13.16/mg | In stock |
| Thymosin Alpha 1 10mgBest per mg | $130.00$13.00/mg | $117.00a vial · $11.70/mg | $110.50a vial · $11.05/mg | $122.20a vial, shipment 2 on · $12.22/mg | In stock |
The 10mg vial works out 7% cheaper per mg than the 5mg. Volume tiers are per size and do not combine across sizes (see bulk pricing). Subscribe & Save takes 6% every month, 4% every 2 months or 2% every 3 months off from shipment 2, two shipments minimum, and stacks on the volume tier: the lowest this record ever bills is $10.39 per mg, twenty 10mg vials on a monthly subscription from shipment 2 onward.
Nothing is added at checkout except the USPS shipping you choose; dispatch and delivery are the same on every order. The cost-per-milligram tool ranks the whole catalogue by price per mg.
Where to buy Thymosin Alpha 1: what to check before you order from anyone
Where to get Thymosin Alpha 1, and how to buy Thymosin Alpha 1 online
Thymosin Alpha 1 for sale, or Thymosin Alpha 1 peptide for sale, means this page: one record, 2 sizes. You can buy Thymosin Alpha 1 online here with guest checkout, and purchase Thymosin Alpha 1 or order Thymosin Alpha 1 in any size below; verified in-stock orders placed before 12 PM Pacific are dispatched the same day. A Thymosin Alpha 1 supplier, vendor or source worth using will show you the lot number and where its certificate can be verified.
Before ordering Thymosin Alpha 1 from anyone, us included, run the 5 checks on verifying a certificate; the first is that the report resolves on the laboratory's own site, and a seller who cannot pass them is asking for the trust a certificate exists to replace.
Thymosin Alpha 1 nasal spray, capsules or oral form? What this vial is, and is not
Search results for Thymosin Alpha 1 also show nasal spray, capsules, oral form products, under listing titles such as thymosin alpha 1 nasal spray, thymosin alpha 1 capsules, thymosin alpha 1 oral, thymosin alpha 1 tablets, thymosin alpha-1 10mg vial. Those are finished consumer goods made and marketed by other companies, and none of them is what this page sells. This record is freeze-dried Thymosin Alpha 1 in a sealed glass vial, 5mg and 10mg, with a lot certificate, supplied for laboratory work. Its certificate describes that powder, not a capsule, spray or cream, which carry other ingredients and sit under different rules.
Thymosin Alpha 1 vs TB-500 and Thymalin/Thymulin: different molecules, separate records
Thymosin Alpha 1 vs TB-500, or TB-500 vs Thymosin Alpha 1, is the comparison people search most, with Thymalin close behind, and they are not the same thing. Each is a different molecule with a different formula, mass and research record, and each has its own certificate here.
TB-500 vs Thymosin Alpha 1: the same comparison, side by side
| Record | Class | Formula | Avg. mass | Sizes here |
|---|---|---|---|---|
| Thymosin Alpha-1 | A 28-residue acetylated peptide originally isolated from thymic tissue; the pharmaceutical form is called thymalfasin. | C129H215N33O55 | 3108.3 | 5mg · 10mg from $70.00 |
| TB-500 | A man-made peptide matching a section of thymosin beta-4. | C38H68N10O14 | 889 | 5mg · 10mg from $54.00 |
| Thymalin/Thymulin | A product name covering two distinct substances: Thymalin, a thymus-derived peptide preparation from the Khavinson series, and thymulin, a characterised zinc-dependent nonapeptide thymic hormone. | C33H54N12O15 | 858.9 | 10mg from $80.00 |
Documentation compared in full: Thymosin Alpha 1 vs TB-500, side by side.
Thymosin Alpha 1 guides and documentation
Written to answer the questions that come up around Thymosin Alpha 1 specifically, what its paperwork should show, how it is handled, and how to judge a supplier selling it.
- Thymosin Alpha-1 certificates of analysis, field by field, and how to check one at the lab
- Thymosin Alpha-1 Identity Testing: How It Is Confirmed
- Thymosin Alpha-1 Storage and Stability in the Laboratory
The full library, grouped by what you came to answer, is in the laboratory guides.
The Thymosin Alpha 1 certificate: lot, purity, identity, and how to verify it
A certificate answers identity, purity and net content as three separate questions, each with the method that produced it and the date it was run, how to read one covers what each field does and does not cover. For Thymosin Alpha 1 that means a mass spectrum landing on 3,108.3 g/mol for C129H215N33O55, the figure published against PubChem CID 16130571.
Listings elsewhere describe Thymosin Alpha-1 as an acetate, an arginate salt or an N-acetyl form. Those are different chemical forms with different masses, and a certificate identifies which one was actually tested. The form of the lot on this page is whatever its certificate states; it is not assumed from a listing name, ours included.
Thymosin Alpha-1 certificates post here and in the certificate index when Kovera Labs reports on the lot.
Solution arithmetic for the bench, with no administration guidance: the vial concentration calculator, preset to Thymosin Alpha-1.
Is Thymosin Alpha 1 legal? FDA status, and what this listing is
FDA status, and what this listing is Not an FDA-approved drug product
The FDA has not approved this compound for anything, and nothing in this catalogue is a medicine.
Status verified 2026-08-25. Check the primary source before relying on this summary.
Whether Thymosin Alpha 1 is legal depends on what it is being used for and where. It is sold as laboratory material under the research-use restriction below. Being listed is not an approval, and not a claim that it is safe, effective or right for any purpose. LabFirst is not a pharmacy or a compounding facility, this vial is not a compounded medicine, and no prescription is involved, because it is not sold for use in anyone.
Thymosin Alpha 1 research: what the published studies examine
Status: No FDA-approved application. This compound is sold as laboratory material. Where research on it has been published, it sits at the animal, cell or early-human stage, and this record does not summarise what it found. A supplier is not a neutral judge of evidence about its own catalogue.
Thymosin alpha 1 is a 28-residue peptide originally isolated from thymic tissue as the fraction responsible for restoring immune function in thymectomised mice — which is a clean origin story, because the assay defined the molecule rather than the other way round. Its mechanism is genuinely pleiotropic rather than lazily described as such: it acts through Toll-like receptors on both myeloid and plasmacytoid dendritic cells, and the downstream effect is activation of signalling pathways and cytokine production across multiple immune cell subsets.
That places it among the better-characterised immune peptides on this catalogue. It is worth distinguishing it clearly from the other thymic materials sold here — it is a single defined 28-residue sequence, unlike Thymalin, which is a tissue extract, and unlike thymulin, which is a zinc-dependent nonapeptide.
| Reported observation | Model | Source |
|---|---|---|
| Originally isolated from thymic tissue as the compound responsible for restoring immune function to thymectomised mice. It has a pleiotropic mechanism affecting multiple immune cell subsets involved in immune suppression, acting through Toll-like receptors in both myeloid and plasmacytoid dendritic cells, leading to activation of signalling pathways and initiation of immune-related cytokine production. | review of preclinical and clinical work | King and Tuthill, Immune modulation with thymosin alpha 1 treatment, Vitamins and Hormones (2016)Both authors were at SciClone Pharmaceuticals, which markets the compound. The mechanism description is standard; the therapeutic framing is not neutral. |
Open questions. The receptor-level mechanism is reasonably well described and the compound has a long history, but two things should temper how the evidence reads. The most accessible review is written by employees of the company that markets it, which does not make the mechanism wrong but does mean the therapeutic framing should be checked against independent sources.
And there is a persistent gap in this literature between demonstrated changes in immune cell subsets and demonstrated changes in clinical outcomes — measuring that lymphocyte populations shift is easier than showing that patients do better, and the first is much more consistently reported than the second. It is registered in a number of countries and not approved in the United States. As a defined 28-residue peptide it is at least analytically tractable, which is more than can be said for the thymic extracts sold alongside it.
Each row above describes an observation in the stated model. None of it describes what Thymosin Alpha-1 would do in a person or an animal outside that model, and none of it is a recommendation to use it for anything.
How to store Thymosin Alpha 1: refrigeration and shelf life
Keep the sealed vial cold and out of the light and it stays as it left the lab. Once it is mixed into a solution, how long it holds up depends on the compound, what it was mixed with, how strong the solution is and how cold it is kept — too many variables for anyone to print one shelf life on a label. So laboratories write the date on whatever they prepare and keep their own record of it.
For solution preparation arithmetic on the bench, concentration, per-graduation values and molarity, use the vial concentration calculator, which opens with the Thymosin Alpha-1 sizes stocked here already loaded. It covers laboratory measurement only and contains no administration guidance.
