SS-31 is a man-made four-building-block peptide that gathers in mitochondria, also published as elamipretide (formula C32H49N9O5, average mass 639.8 g/mol, CAS 736992-21-5). SS-31 is sold here for laboratory research in 2 sizes (10mg to 50mg), from $59.00 a vial. It is not an FDA-approved medicine. Research use only, and never for people or animals.
SS-31 specifications
| Product name | SS-31 |
|---|---|
| Also sold as | Elamipretide, MTP-131, SS-31 peptide |
| Formula | C32H49N9O5 |
| Average mass | 639.8 g/mol |
| CAS number | 736992-21-5 |
| Physical form | Freeze-dried powder, a solid cake in a sealed vial |
| Appearance | White to off-white cake |
| Sizes on this page | 10mg · 50mg |
| Purity specification | ≥99% by RP-HPLC. The number for the lot you receive is whatever its own certificate says. |
| Identity check | Mass spectrometry, read against the mass this compound should have |
| Net content | Weighed per lot and reported separately from purity |
| Lot documentation | 2 of 2 sizes have a published Kovera Labs certificate (10mg, lot LF-26A-2609; 50mg, lot LF-26B-2609) |
| Storage | Sealed, cold and out of the light |
| Ships from | Santa Ana, California by USPS with tracking on every order, same business day on verified in-stock orders placed before 12 PM Pacific |
| Intended use | Laboratory research only. Not for human or animal use. |
What is SS-31, and what is it used for?
SS-31 is also listed and searched as Elamipretide, MTP-131, SS-31 peptide. They all mean the same compound. Supplier lists write it as SS-31 peptides or peptide SS-31 as well; every one of those is this record. A name is not a test, which is why the lot record further down counts for more than the wording on a label.
Chemically: molecular formula C32H49N9O5, average mass 639.8 g/mol (PubChem CID 11764719). Those figures are what the identity test on a certificate is read against.
A man-made four-building-block peptide that gathers in mitochondria, also published as elamipretide.
Described in the research as sticking to cardiolipin, a fat molecule in the inner membrane of mitochondria. Its alternating pattern of bulky and positively charged building blocks is the feature associated with it ending up there.
Animal and clinical-stage research on mitochondria and on cardiolipin.
No approved product. SS-31 and elamipretide are two names for the same peptide, and certificates may use either; that is a naming difference, not a chemical one.
SS-31 for sale: 10mg and 50mg vials, price per mg
SS-31 is sold in 2 sizes here, 10mg and 50mg, from $59.00 a vial. SS-31 cost and SS-31 price per mg by size are in the table, at each volume tier and on subscription; the per-mg figure under each price is the one that compares across sizes.
Volume and subscription pricing by size
| Size | One vial | 10–19 vials−10% | 20 vials−15% | Subscribe monthly−6% from shipment 2 | Availability |
|---|---|---|---|---|---|
| SS-31 10mg | $59.00$5.90/mg | $53.10a vial · $5.31/mg | $50.15a vial · $5.01/mg | $55.46a vial, shipment 2 on · $5.55/mg | In stock |
| SS-31 50mgBest per mg | $209.00$4.18/mg | $188.10a vial · $3.76/mg | $177.65a vial · $3.55/mg | $196.46a vial, shipment 2 on · $3.93/mg | In stock |
The 50mg vial works out 29% cheaper per mg than the 10mg. Volume tiers are per size and do not combine across sizes (see bulk pricing). Subscribe & Save takes 6% every month, 4% every 2 months or 2% every 3 months off from shipment 2, two shipments minimum, and stacks on the volume tier: the lowest this record ever bills is $3.34 per mg, twenty 50mg vials on a monthly subscription from shipment 2 onward.
Nothing is added at checkout except the USPS shipping you choose; dispatch and delivery are the same on every order. The cost-per-milligram tool ranks the whole catalog by price per mg. The certificate walked through field by field: Where to Buy SS-31 Peptide: Five Checks Before You Order.
Where to buy SS-31: what to check before you order from anyone
Where to get SS-31, and how to buy SS-31 online
SS-31 for sale, or SS-31 peptide for sale, means this page: one record, 2 sizes. You can buy SS-31 online here with guest checkout, and purchase SS-31 or order SS-31 in any size below; verified in-stock orders placed before 12 PM Pacific are dispatched the same day. If the question is where to get SS-31 or how to get SS-31, the answer for a US laboratory is a supplier who publishes the certificate before you pay, which is the first of the five checks that follow.
Before ordering SS-31 from anyone, us included, run the 5 checks on verifying a certificate; the first is that the report resolves on the laboratory's own site, and a seller who cannot pass them is asking for the trust a certificate exists to replace.
SS-31 nasal spray, capsules or oral form? What this vial is, and is not
Search results for SS-31 also show nasal spray, capsules, oral form products, under listing titles such as ss 31 peptide nasal spray, ss 31 300mg vial, ss 31 peptide capsules, ss 31 peptide oral, ss-31 nasal spray. Those are finished consumer goods made and marketed by other companies, and none of them is what this page sells. This record is freeze-dried SS-31 in a sealed glass vial, 10mg and 50mg, with a lot certificate, supplied for laboratory work. Its certificate describes that powder, not a capsule, spray or cream, which carry other ingredients and sit under different rules.
SS-31 vs MOTS-c (Human): different molecules, separate records
SS-31 vs MOTS-c, or MOTS-c vs SS-31, is the comparison people search most, and they are not the same thing. Each is a different molecule with a different formula, mass and research record, and each has its own certificate here.
MOTS-c vs SS-31: the same comparison, side by side
| Record | Class | Formula | Avg. mass | Sizes here |
|---|---|---|---|---|
| SS-31 | A man-made four-building-block peptide that gathers in mitochondria, also published as elamipretide. | C32H49N9O5 | 639.8 | 10mg · 50mg from $59.00 |
| MOTS-c (Human) | A 16-building-block peptide whose recipe is written in mitochondrial DNA. | C101H152N28O22S2 | 2174.6 | 10mg · 20mg · 40mg from $60.00 |
Documentation compared in full: SS-31 vs MOTS-c, side by side.
SS-31 guides and documentation
Written to answer the questions that come up around SS-31 specifically, what its paperwork should show, how it is handled, and how to judge a supplier selling it.
- SS-31 certificates of analysis, field by field, and how to check one at the lab
- SS-31 identity testing: what the mass spectrum fixes, and what it leaves open
- SS-31 storage and stability: what shortens the shelf life, and what protects it
- Where to buy SS-31 Peptide: reading the listing and the lot record
The full library, grouped by what you came to answer, is in the laboratory guides.
The SS-31 certificate: lot, purity, identity, and how to verify it
A certificate answers identity, purity and net content as three separate questions, each with the method that produced it and the date it was run, how to read one covers what each field does and does not cover. For SS-31 that means a mass spectrum landing on 639.8 g/mol for C32H49N9O5, the figure published against PubChem CID 11764719. The cataloged form is Elamipretide, and the identity test resolves to that rather than to a related molecule with a similar name.
Listings elsewhere describe SS-31 as an acetate, an arginate salt or an N-acetyl form. Those are different chemical forms with different masses, and a certificate identifies which one was actually tested. The form of the lot on this page is whatever its certificate states; it is not assumed from a listing name, ours included.
| Size | Lot | Identity method | Purity | Endotoxin · sterility · fentanyl | Test date |
|---|---|---|---|---|---|
| 10mg | LF-26A-2609 | LC-MS | 99.828% (RP-HPLC, C18, DAD @ 214 nm) | 2026-09-29 | |
| 50mg | LF-26B-2609 | LC-MS | 99.736% (RP-HPLC, C18, DAD @ 214 nm) | 2026-09-29 |
Testing by Kovera Labs. Every batch tested on or after October 1, 2026 includes endotoxin, sterility and fentanyl screening, in addition to identity, purity and net content. Open the report, then confirm it on the issuing laboratory's own site. If the identifier does not resolve there, or resolves to a different lot than the one printed on your vial, the document is worthless however convincing it looks.
- Certificate for lot LF-26A-2609 · Report PDF · Verify at Kovera Labs
- Certificate for lot LF-26B-2609 · Report PDF · Verify at Kovera Labs
The lot number on the certificate must match the lot printed on the vial you received. That match is the only thing tying the document to your material. Net content is reported separately from purity, because a vial can be highly pure and still hold less material than its label states.
Solution arithmetic for the bench, with no administration guidance: the vial concentration calculator, preset to SS-31.
Where the FDA stands on SS-31
FDA status, and what this listing is Not an FDA-approved drug product
The FDA has not approved this compound for anything, and nothing in this catalog is a medicine.
Status verified 2026-08-25. Check the primary source before relying on this summary.
It is sold as laboratory material under the research-use restriction below. Being listed is not an approval, and not a claim that it is safe, effective or right for any purpose.
SS-31 research: what the published studies examine
Status: No FDA-approved application. This compound is sold as laboratory material. Where research on it has been published, it sits at the animal, cell or early-human stage, and this record does not summarize what it found. A supplier is not a neutral judge of evidence about its own catalog.
SS-31 is a man-made four-building-block peptide from the Szeto-Schiller series, and it turns up in the literature under several names including elamipretide, MTP-131 and Bendavia. Its mechanism is unusual because the target is a fat molecule rather than a protein. It sticks to cardiolipin, the negatively charged fat in the inner membrane of mitochondria that the folded shelves inside them depend on. Its positively charged building blocks are drawn to cardiolipin’s charged heads and its bulky ones tuck into the greasy tails.
Since cardiolipin gathering in one spot helps the membrane curve the way those folds need, sticking to it is proposed to hold that structure together. The alternating bulky-and-charged pattern is what carries the peptide through membranes and concentrates it in mitochondria; it is a design feature of the series rather than an accident.
| Reported observation | Model | Source |
|---|---|---|
| SS-31 interacts with cardiolipin and speeds the recovery of ATP, the cell’s energy currency, in mitochondria starved of blood. Less acute kidney injury was reported in the model. | ischaemia-reperfusion, rodent kidney | Birk and colleagues, The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin, Journal of the American Society of Nephrology (2013) |
| SS-31 binds model membranes and changes the electrical charge at their surface, presented as a core part of the mechanism rather than a downstream consequence. | model lipid bilayers and biophysical assay | Mitchell and colleagues, The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics, Journal of Biological Chemistry (2020) |
| After blood flow was cut off and restored in rat hearts, the internal folds of mitochondria broke up less in treated animals, connecting the cardiolipin mechanism to a visible change in mitochondrial structure under the microscope. | rat cardiac ischaemia-reperfusion, electron microscopy | The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats, Communications Biology (2020) |
Open questions. The biophysics is well described and the animal work is consistent, but elamipretide has been through human trials under a sponsor and the results across different conditions have been mixed rather than uniformly good. Any description of this compound that reports only the favorable animal picture is picking and choosing. The peptide sold as SS-31 and the clinical drug elamipretide are the same sequence, which means the clinical record is relevant to reading the animal claims, and it is routinely left out when it is not flattering.
Each row above describes an observation in the stated model. None of it describes what SS-31 would do in a person or an animal outside that model, and none of it is a recommendation to use it for anything.
How to store SS-31: refrigeration and shelf life
Keep the sealed vial cold and out of the light and it stays as it left the lab. Once it is mixed into a solution, how long it holds up depends on the compound, what it was mixed with, how strong the solution is and how cold it is kept — too many variables for anyone to print one shelf life on a label. So laboratories write the date on whatever they prepare and keep their own record of it.
For solution preparation arithmetic on the bench, concentration, per-graduation values and molarity, use the vial concentration calculator, which opens with the SS-31 sizes stocked here already loaded. It covers laboratory measurement only and contains no administration guidance.
