This page compares what is documented about Dulaglutide and Semaglutide, rather than ranking them by effect. What each molecule is, the sizes and prices actually carried, what the certificate covers, and how the two differ on the bench. Everything here is research-use-only material and we do not publish outcome, dosing or administration content for any compound in the catalogue.
What is Dulaglutide and what is Semaglutide?
Dulaglutide. Dulaglutide is a GLP-1 receptor agonist built as a fusion to an immunoglobulin Fc fragment, which puts it at protein scale rather than peptide scale.
Semaglutide. Semaglutide is the most-cited GLP-1 receptor agonist in the research literature, which makes verified reference material a staple for comparative receptor work.
How do Dulaglutide and Semaglutide compare on price and size?
| Dulaglutide | Semaglutide | |
|---|---|---|
| Sizes carried | 5 mg, 10 mg | 5 mg, 10 mg, 15 mg, 20 mg, 30 mg |
| From | $130.00 | $80.00 |
| Best price per unit | $13.50 / mg | $3.83 / mg |
| Availability | Backordered — waitlist | Backordered — waitlist |
| Certificate | Lot certificate on the product page | Lot certificate on the product page |
| Molecular formula | — | C187H291N45O59 |
| Molar mass | — | 4,114 g/mol |
| Source | — | PubChem CID 56843331 |
| Research area | incretin receptor pharmacology | GLP-1 receptor research |
At their best sizes Semaglutide works out at $3.83 per mg against $13.50 for Dulaglutide — 3.5 times more for the mg. Vial prices start at $130.00 and $80.00 respectively, which is the number most people compare and the one that says least, because the two are not sold in the same sizes. Full sizes, tier pricing and the lot certificate sit on the Dulaglutide page and the Semaglutide page.
What is each one studied for?
What the published literature investigates, which is a different question from what either will do, and the only one of the two a supplier can answer.
Dulaglutide is studied in incretin receptor pharmacology research. Fc fusion is one of the most widely used half-life extension strategies in the protein literature.
Semaglutide is studied in glp-1 receptor research. GLP-1 receptor biology continues to dominate metabolic-research publishing, and semaglutide remains its most-cited reference compound.
Studied in the same area does not make two compounds interchangeable, and the research library holds the per-compound documentation.
Semaglutide vs Dulaglutide: how they differ on the bench
Semaglutide. Semaglutide degrades along predictable routes — our stability guide maps which storage regime suits sealed powder versus a working solution.
Dulaglutide. Fc fusions are large, glycosylation-sensitive and nothing like a synthetic peptide in handling. Methods and storage advice written for short chains do not apply.
What actually differs between Semaglutide and Dulaglutide
Molar mass is not published for both of these, so the mass-to-amount conversion below is left undone rather than estimated. Where a formula and a molecular weight exist they are in the table above, carried with the PubChem record they came from; where they are not, the lot certificate is the document that settles what the material is.
Identity is the other analytical axis, and it is settled per lot rather than per compound. Dulaglutide. Dulaglutide is a GLP-1 analogue fused to an antibody Fc region, not GLP-1 itself. UniProt P01275 is the human precursor that native GLP-1 comes from, given for reference; the fusion is a larger glycosylated protein whose mass the lot certificate reports. Semaglutide. Catalogued as Semaglutide, and the certificate's identity test resolves to that.
Both are released against a certificate reporting identity, purity by the stated method and net peptide content, readable before anything is bought.
Which is better, Semaglutide or Dulaglutide?
Neither Semaglutide nor Dulaglutide is ranked against the other here, and the refusal is deliberate. Better, safer and stronger are questions about effects in a living system, and we sell neither compound for use in one — why none of these pages ranks two compounds sets out the reasoning in full.
What it does instead, for these two:
- Semaglutide is the cheaper of the two per mg, at $3.83 against $13.50.
- Dulaglutide is carried in 2 sizes and Semaglutide in 5, and each lot carries its own certificate.
Every one of those is checkable before you buy.
Common questions
What is the difference between Semaglutide and Dulaglutide?
Semaglutide is the most-cited GLP-1 receptor agonist in the research literature, which makes verified reference material a staple for comparative receptor work. Dulaglutide is a GLP-1 receptor agonist built as a fusion to an immunoglobulin Fc fragment, which puts it at protein scale rather than peptide scale.
Which one should I choose?
Dulaglutide is carried in 5 mg, 10 mg and Semaglutide in 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, each lot with its own certificate. Which of those suits the work is yours to decide; everything here is research-use-only rather than guidance for use in a human or an animal.
Do both Dulaglutide and Semaglutide come with a certificate of analysis?
Neither is in stock at the moment, so in each case the certificate is the one attached to the lot that arrives. A certificate belongs to a lot, not to a product. It is linked from the product page, and reports identity, purity by the stated method, and net peptide content for the material actually in that lot.
Which is cheaper, Semaglutide or Dulaglutide?
Per mg, Semaglutide at $3.83 against $13.50, taking each one's best size. By vial they start at $130.00 for Dulaglutide and $80.00 for Semaglutide, which is the comparison most people make and the one that says least, because the two are not sold in the same sizes.
FOR LABORATORY AND IN-VITRO RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR PERSONAL, MEDICAL, DIAGNOSTIC, THERAPEUTIC, OR RECREATIONAL USE.