This page compares what is documented about IGF-1 LR3 and Tesamorelin, rather than ranking them by effect. What each molecule is, the sizes and prices actually carried, what the certificate covers, and how the two differ on the bench. Everything here is research-use-only material and we do not publish outcome, dosing or administration content for any compound in the catalogue.
What is IGF-1 LR3 and what is Tesamorelin?
IGF-1 LR3. IGF-1 LR3 is an analogue of insulin-like growth factor 1 carrying an extended N-terminus and a substitution at position 3, a pairing that reduces its affinity for the binding proteins that otherwise dominate IGF-1 behaviour in solution.
Tesamorelin. Tesamorelin is a stabilised GHRH(1-44) analogue whose trans-3-hexenoyl modification resists DPP-4 cleavage — a textbook case study in peptide half-life engineering.
How do IGF-1 LR3 and Tesamorelin compare on price and size?
| IGF-1 LR3 | Tesamorelin | |
|---|---|---|
| Sizes carried | 0.1 mg, 1 mg | 5 mg, 10 mg, 20 mg |
| From | $65.00 | $45.00 |
| Best price per unit | $95.00 / mg | $7.50 / mg |
| Availability | Backordered — waitlist | Backordered — waitlist |
| Certificate | Lot certificate on the product page | Lot certificate on the product page |
| Molecular formula | — | C221H366N72O67S |
| Molar mass | — | 5,136 g/mol |
| Source | — | PubChem CID 16137828 |
| Research area | growth factor signalling | GHRH-axis research |
At their best sizes Tesamorelin works out at $7.50 per mg against $95.00 for IGF-1 LR3 — 12.7 times more for the mg. Vial prices start at $65.00 and $45.00 respectively, which is the number most people compare and the one that says least, because the two are not sold in the same sizes. Full sizes, tier pricing and the lot certificate sit on the IGF-1 LR3 page and the Tesamorelin page.
What is each one studied for?
What the published literature investigates, which is a different question from what either will do, and the only one of the two a supplier can answer.
IGF-1 LR3 is studied in growth factor signalling research. Growth factor signalling remains one of the most heavily published areas in cell biology, and analogue design is where much of the current method work sits.
Tesamorelin is studied in ghrh-axis research. GHRH-axis research remains steady, and tesamorelin's engineered stability keeps it the reference analogue in that literature.
Studied in the same area does not make two compounds interchangeable, and the research library holds the per-compound documentation.
Tesamorelin vs IGF-1 LR3: how they differ on the bench
Tesamorelin. Tesamorelin's stabilising modification is exactly what our identity testing confirms — the unmodified sequence would pass a naive mass check at a glance.
IGF-1 LR3. Binding-protein affinity is the whole reason this analogue exists, so anything that alters the protein in solution alters the experiment. Sealed, desiccated and dark is the baseline; our storage guide covers why water is the first variable to control.
What actually differs between Tesamorelin and IGF-1 LR3
Molar mass is not published for both of these, so the mass-to-amount conversion below is left undone rather than estimated. Where a formula and a molecular weight exist they are in the table above, carried with the PubChem record they came from; where they are not, the lot certificate is the document that settles what the material is.
Identity is the other analytical axis, and it is settled per lot rather than per compound. IGF-1 LR3. IGF-1 LR3 is an ANALOGUE of IGF-1, not IGF-1 itself: an arginine substitution at position 3 plus a 13-residue N-terminal extension. UniProt P05019 is the parent protein for reference; the analogue has its own mass, which the lot certificate reports. Tesamorelin. Catalogued as Tesamorelin, and the certificate's identity test resolves to that.
Both are released against a certificate reporting identity, purity by the stated method and net peptide content, readable before anything is bought.
Which is better, Tesamorelin or IGF-1 LR3?
Neither Tesamorelin nor IGF-1 LR3 is ranked against the other here, and the refusal is deliberate. Better, safer and stronger are questions about effects in a living system, and we sell neither compound for use in one — why none of these pages ranks two compounds sets out the reasoning in full.
What it does instead, for these two:
- Tesamorelin is the cheaper of the two per mg, at $7.50 against $95.00.
- IGF-1 LR3 is carried in 2 sizes and Tesamorelin in 3, and each lot carries its own certificate.
Every one of those is checkable before you buy.
Common questions
What is the difference between Tesamorelin and IGF-1 LR3?
Tesamorelin is a stabilised GHRH(1-44) analogue whose trans-3-hexenoyl modification resists DPP-4 cleavage — a textbook case study in peptide half-life engineering. IGF-1 LR3 is an analogue of insulin-like growth factor 1 carrying an extended N-terminus and a substitution at position 3, a pairing that reduces its affinity for the binding proteins that otherwise dominate IGF-1 behaviour in solution.
Which one should I choose?
IGF-1 LR3 is carried in 0.1 mg, 1 mg and Tesamorelin in 5 mg, 10 mg, 20 mg, each lot with its own certificate. Which of those suits the work is yours to decide; everything here is research-use-only rather than guidance for use in a human or an animal.
Do both IGF-1 LR3 and Tesamorelin come with a certificate of analysis?
Neither is in stock at the moment, so in each case the certificate is the one attached to the lot that arrives. A certificate belongs to a lot, not to a product. It is linked from the product page, and reports identity, purity by the stated method, and net peptide content for the material actually in that lot.
Which is cheaper, Tesamorelin or IGF-1 LR3?
Per mg, Tesamorelin at $7.50 against $95.00, taking each one's best size. By vial they start at $65.00 for IGF-1 LR3 and $45.00 for Tesamorelin, which is the comparison most people make and the one that says least, because the two are not sold in the same sizes.
FOR LABORATORY AND IN-VITRO RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR PERSONAL, MEDICAL, DIAGNOSTIC, THERAPEUTIC, OR RECREATIONAL USE.