Pinealon is short synthetic peptide from the Khavinson "bioregulator" series (formula C15H26N6O8, average mass 418.4 g/mol, CAS 175175-23-2). Pinealon is sold here for laboratory research in 2 sizes (10mg to 20mg), from $60.00 a vial. It is not an FDA-approved medicine. Research use only, and never for people or animals.
Pinealon specifications
| Product name | Pinealon |
|---|---|
| Formula | C15H26N6O8 |
| Average mass | 418.4 g/mol |
| CAS number | 175175-23-2 |
| Physical form | Freeze-dried powder, a solid cake in a sealed vial |
| Appearance | White to off-white cake |
| Sizes on this page | 10mg · 20mg |
| Purity specification | ≥99% by RP-HPLC. The number for the lot you receive is whatever its own certificate says. |
| Identity check | Mass spectrometry, read against the mass this compound should have |
| Net content | Weighed per lot and reported separately from purity |
| Lot documentation | Tested by Kovera Labs; each lot's certificate posts here when it is reported |
| Storage | Sealed, cold and out of the light |
| Ships from | Santa Ana, California by USPS with tracking on every order, same business day on verified in-stock orders placed before 12 PM Pacific |
| Intended use | Laboratory research only. Not for human or animal use. |
What is Pinealon, and what is it used for?
Supplier lists write it as Pinealon peptides or peptide Pinealon; every one of those is this record, and the lot certificate further down counts for more than the wording on a label.
Chemically: molecular formula C15H26N6O8, average mass 418.4 g/mol (PubChem CID 10273502). Those figures are what the identity test on a certificate is read against.
Short synthetic peptide from the Khavinson "bioregulator" series.
Mechanism is not established in the conventional receptor sense. The originating group proposes that these peptides act epigenetically, entering cells and binding directly to specific DNA sequences to modulate transcription of tissue-relevant genes, with molecular docking used as the supporting method. That is a hypothesis about a mechanism, not a demonstrated pathway, and it has not been independently confirmed outside the groups that advanced it.
Appears in a preclinical literature of organotypic tissue culture, rodent models and gene-expression work, largely produced by the St Petersburg Institute of Bioregulation and Gerontology and collaborating Russian institutes. A substantial share is published in Russian, in journals with limited international circulation.
No approved product outside Russia, no pharmacopeial monograph, no independently replicated mechanism, and no controlled trial meeting United States or European standards. The volume of commercial writing about this series greatly exceeds what its cited sources report.
Pinealon for sale: 10mg and 20mg vials, price per mg
Pinealon is sold in 2 sizes here, 10mg and 20mg, from $60.00 a vial. Pinealon cost and Pinealon price per mg by size are in the table, at each volume tier and on subscription; the per-mg figure under each price is the one that compares across sizes.
Volume and subscription pricing by size
| Size | One vial | 10–19 vials−10% | 20 vials−15% | Subscribe monthly−6% from shipment 2 | Availability |
|---|---|---|---|---|---|
| Pinealon 10mg | $60.00$6.00/mg | $54.00a vial · $5.40/mg | $51.00a vial · $5.10/mg | $56.40a vial, shipment 2 on · $5.64/mg | Backordered — waitlist |
| Pinealon 20mg | $85.00$4.25/mg | $76.50a vial · $3.83/mg | $72.25a vial · $3.61/mg | $79.90a vial, shipment 2 on · $3.99/mg | Backordered — waitlist |
Volume tiers are per size and do not combine across sizes (see bulk pricing). Subscribe & Save takes 6% every month, 4% every 2 months or 2% every 3 months off from shipment 2, two shipments minimum, and stacks on the volume tier: the lowest this record ever bills is $4.79 per mg, twenty 10mg vials on a monthly subscription from shipment 2 onward.
Nothing is added at checkout except the USPS shipping you choose; dispatch and delivery are the same on every order. The cost-per-milligram tool ranks the whole catalog by price per mg.
Where to buy Pinealon: what to check before you order from anyone
Pinealon for sale, or Pinealon peptide for sale, means this page: one record, 2 sizes. You can buy Pinealon online here with guest checkout; verified in-stock orders placed before 12 PM Pacific are dispatched the same day.
Before ordering Pinealon from anyone, us included, run the 5 checks on verifying a certificate; the first is that the report resolves on the laboratory's own site, and a seller who cannot pass them is asking for the trust a certificate exists to replace.
Pinealon capsules or oral form? What this vial is, and is not
Search results for Pinealon also show capsules, oral form products, under listing titles such as pinealon peptide capsules, pinealon peptide oral. Those are finished consumer goods made and marketed by other companies, and none of them is what this page sells. This record is freeze-dried Pinealon in a sealed glass vial, 10mg and 20mg, with a lot certificate, supplied for laboratory work. Its certificate describes that powder, not a capsule, spray or cream, which carry other ingredients and sit under different rules.
Pinealon vs Epithalon: different molecules, separate records
Pinealon vs Epitalon, or Epitalon vs Pinealon, is the comparison people search most, and they are not the same thing. Each is a different molecule with a different formula, mass and research record, and each has its own certificate here.
Epitalon vs Pinealon: the same comparison, side by side
| Record | Class | Formula | Avg. mass | Sizes here |
|---|---|---|---|---|
| Pinealon | Short synthetic peptide from the Khavinson "bioregulator" series. | C15H26N6O8 | 418.4 | 10mg · 20mg from $60.00 |
| Epithalon | A man-made peptide of four building blocks. | C14H22N4O9 | 390.35 | 10mg · 50mg from $40.00 |
Documentation compared in full: Pinealon vs Epitalon, side by side.
The Pinealon certificate: lot, purity, identity, and how to verify it
A certificate answers identity, purity and net content as three separate questions, each with the method that produced it and the date it was run, how to read one covers what each field does and does not cover. For Pinealon that means a mass spectrum landing on 418.4 g/mol for C15H26N6O8, the figure published against PubChem CID 10273502.
Pinealon certificates post here and in the certificate index when Kovera Labs reports on the lot.
Solution arithmetic for the bench, with no administration guidance: the vial concentration calculator, preset to Pinealon.
Is Pinealon a prescription drug? FDA status, and what this listing is
FDA status, and what this listing is Not an FDA-approved drug product
The FDA has not approved this compound for anything, and nothing in this catalog is a medicine.
Status verified 2026-08-25. Check the primary source before relying on this summary.
It is sold as laboratory material under the research-use restriction below. Being listed is not an approval, and not a claim that it is safe, effective or right for any purpose. LabFirst is not a pharmacy or a compounding facility, this vial is not a compounded medicine, and no prescription is involved, because it is not sold for use in anyone.
Pinealon research: what the published studies examine
Status: No FDA-approved application. This compound is sold as laboratory material. Where research on it has been published, it sits at the animal, cell or early-human stage, and this record does not summarize what it found. A supplier is not a neutral judge of evidence about its own catalog.
Pinealon is the tripeptide Glu-Asp-Arg, confirmed as that sequence in the primary literature rather than only in vendor material. It is the pineal-associated member of the series and the one with the most published work outside the originating institute. The originating group proposes that these peptides act epigenetically, entering cells and binding directly to specific DNA sequences to modulate transcription of tissue-relevant genes, with molecular docking used as the supporting method.
That is a hypothesis about a mechanism, not a demonstrated pathway, and it has not been independently confirmed outside the groups that advanced it. The series was developed at the St Petersburg Institute of Bioregulation and Gerontology, and the design premise is tissue specificity: each short peptide is claimed to act on the organ its parent extract came from. That premise rests principally on explant-outgrowth assays from the same group.
| Reported observation | Model | Source |
|---|---|---|
| In offspring of rats with experimental hyperhomocysteinaemia induced by dietary methionine loading during pregnancy, pinealon (Glu-Asp-Arg) administration was associated with improved spatial orientation and learning in the offspring, reduced reactive oxygen species accumulation, and fewer necrotic cells among neurons isolated from offspring cerebellum. | rat prenatal hyperhomocysteinaemia model, offspring behavior and isolated cerebellar neurons | Arutjunyan and colleagues, Pinealon protects the rat offspring from prenatal hyperhomocysteinemia, International Journal of Clinical and Experimental Medicine (2012)Khavinson is a co-author. The journal has since been discontinued. |
| In a hypobaric hypoxia model comparing vilon, epitalon, vesugen and pinealon, pinealon showed the most pronounced effect. The authors attribute it less to direct suppression of reactive oxygen species than to stimulation of endogenous antioxidant enzymes and possibly limitation of NMDA-mediated excitotoxicity. | rat hypobaric hypoxia, including prenatal hypoxia | Kozina, Investigation of antihypoxic properties of short peptides, Advances in Gerontology (2008)Russian-language paper with an English abstract. |
| Glu-Asp-Arg and Lys-Glu-Asp were reported to stimulate serotonin expression in ageing cultures of brain cortex cells, with molecular docking used to propose that the peptides bind a CCTGCC sequence in the tryptophan hydroxylase gene. | aged rat brain cortex cell culture, with molecular docking | Khavinson and colleagues, Short peptides stimulate serotonin expression in cells of brain cortex, Bulletin of Experimental Biology and Medicine (2014)The DNA-binding claim rests on docking, which predicts an interaction rather than measuring one. |
Open questions. Pinealon has more published work behind it than most of this series, and the prenatal hypoxia and hyperhomocysteinaemia models are real experiments with measured endpoints. Two limitations apply to every compound in this series and are worth stating plainly rather than once at the bottom of a catalog. First, provenance: the great majority of primary work comes from one institute and its collaborators, much of it published in Russian, and independent replication outside that network is scarce.
That is a limit on how confidently the findings can be read, not an allegation about them. Second, the assays: explant outgrowth in organotypic culture and gene-expression shifts in cultured cells are the dominant endpoints, and neither establishes what a compound does in an intact animal, let alone a person. The proposed epigenetic mechanism — short peptides entering the nucleus and binding DNA directly — is supported largely by molecular docking, which is a computational prediction rather than a measurement.
Each row above describes an observation in the stated model. None of it describes what Pinealon would do in a person or an animal outside that model, and none of it is a recommendation to use it for anything.
How to store Pinealon: refrigeration and shelf life
Keep the sealed vial cold and out of the light and it stays as it left the lab. Once it is mixed into a solution, how long it holds up depends on the compound, what it was mixed with, how strong the solution is and how cold it is kept — too many variables for anyone to print one shelf life on a label. So laboratories write the date on whatever they prepare and keep their own record of it.
For solution preparation arithmetic on the bench, concentration, per-graduation values and molarity, use the vial concentration calculator, which opens with the Pinealon sizes stocked here already loaded. It covers laboratory measurement only and contains no administration guidance.
