PEG-MGF is sold here for laboratory research, in 1 size (2mg), starting at $80.00 a vial. Every batch arrives with a certificate naming the test that identified it, the test that measured its purity, and the date each was run. It is not an FDA-approved medicine. Research use only, and never for people or animals.
PEG-MGF specifications
| Product name | PEG-MGF |
|---|---|
| Also sold as | PEG MGF peptide, pegylated mechano growth factor |
| Physical form | Freeze-dried powder — a solid cake in a sealed vial |
| Appearance | White to off-white cake |
| Sizes on this page | 2mg |
| Purity specification | ≥99% by RP-HPLC. The number for the lot you receive is whatever its own certificate says. |
| Identity check | Mass spectrometry, read against the mass this compound should have |
| Net content | Weighed per lot and reported separately from purity |
| Lot documentation | At the laboratory — each certificate posts here the day it clears |
| Storage | Sealed, cold and out of the light |
| Ships from | Santa Ana, California — same business day on verified in-stock orders placed before 12 PM Pacific |
| Intended use | Laboratory research only. Not for human or animal use. |
What is PEG-MGF, and what is it used for?
PEG-MGF is also listed and searched as PEG MGF peptide, pegylated mechano growth factor. They all mean the same compound. Supplier lists write it as PEG-MGF peptides or peptide PEG-MGF as well; every one of those is this record. A name is not a test, which is why the lot record further down counts for more than the wording on a label.
Pegylated synthetic peptide corresponding to the E-domain of the IGF-1Ec splice variant, known as mechano growth factor.
MGF is an alternatively spliced IGF-1 variant induced in skeletal muscle by mechanical overload and injury. The E-domain peptide is proposed to act separately from the IGF-1 receptor, on satellite cell activation, though its receptor has not been identified. Pegylation is a formulation change intended to slow clearance.
Muscle adaptation, satellite cell activation and repair following overload or injury, largely in cell lines and rodent models.
No receptor identified for the E-domain peptide, no approved product, no human trials. The pegylated form specifically has essentially no independent published literature.
PEG-MGF for sale: 2mg vials, price per mg
PEG-MGF is sold in 1 size here, 2mg, from $80.00 a vial. The per-mg column is the honest comparison between sizes; the two tier columns show what ten and twenty vials of one size bill at, because the volume discount is per size and mixed sizes do not combine.
| Size | One vial | Per mg | 10 vials −10% | 20 vials −15% | Availability |
|---|---|---|---|---|---|
| PEG-MGF 2mg | $80.00 | $40.00 | $720.00$36.00/mg | $1,360.00$34.00/mg | Backordered — waitlist |
PEG-MGF discounts: bulk pricing, Subscribe & Save, and codes
Three things move this price and nothing else does: how many vials of one size are on the order, whether that order repeats, and one code. The fourth column prices each route against the 2mg vial.
| Buying option | Takes off | When it applies | 2mg at this option |
|---|---|---|---|
| One vial, one time | — | Any order | $80.00 |
| 10–19 vials of one size | 10% | This order | $720.00$72.00 a vial |
| 20 vials of one size | 15% | This order | $1,360.00$68.00 a vial |
| Subscribe, every 1 month | 6% | Shipment 2 onward | First $80.00, then $75.20 |
| Subscribe, every 2 months | 4% | Shipment 2 onward | First $80.00, then $76.80 |
| Subscribe, every 3 months | 2% | Shipment 2 onward | First $80.00, then $78.40 |
| 10 vials on a monthly subscription | 10%, then 6% more | Shipment 2 onward | First $720.00, then $676.80 |
| Sign-up code | 10% of the order | One use, dead 24 hours after signup | $72.00 for one vial |
| Friday newsletter code | 5% of the order | Live 24 hours, a new one each Friday | $76.00 for one vial |
| On-site offer code | 5% of the order | Live 30 minutes from when it appears | $76.00 for one vial |
| Free standard shipping | The shipping charge | Orders over $200 | 3 vials |
The first three stack; the codes do not. A volume discount comes off the line, a subscription cadence comes off that same line from shipment 2, and one code comes off what is left. One code per order, never two. A subscription runs a minimum of two shipments and can be cancelled once the second has shipped, and the first shipment always bills at today's eligible price with no cadence discount on it. The lowest this record ever bills is $31.96 per mg: twenty 2mg vials on a monthly subscription, from shipment 2 onward.
Every figure above is what you pay; nothing is added at checkout — dispatch and delivery work the same on every order.
Where to buy PEG-MGF: five checks before you order from anyone
Where to get PEG-MGF, and how to buy PEG-MGF online
PEG-MGF for sale, or PEG-MGF peptide for sale, means this page: one record, 1 size, a lot certificate for each. You can buy PEG-MGF online here with guest checkout; verified in-stock orders placed before 12 PM Pacific are dispatched the same day.
Run these on us too. A supplier who cannot pass them is asking you to take their word for it, and their word is the one thing a certificate exists to replace.
- Check the certificate on the lab’s own site, not ours.
- See whether it was written for the seller.
- Match the lot number on the paper to the one on the vial.
- Look for a method and a date next to every number.
- Make sure identity was tested, not assumed.
Each of those is worked through, with what a failed check actually looks like, on verifying a certificate.
The PEG-MGF certificate: lot, purity, identity, and how to verify it
A certificate answers identity, purity and net content as three separate questions, each with the method that produced it and the date it was run — how to read one covers what each field does and does not cover. MGF is a splice variant of IGF-1, and PEG-MGF is that peptide with polyethylene glycol attached. A PEG conjugate has no single molecular mass because PEG is a distribution of chain lengths, which is why no compound record exists. UniProt P05019 is the parent protein for reference. So the mass on the lot certificate is the one to read; a listing that quotes the published figure for this material is quoting the wrong molecule.
The certificate below belongs to one lot, and its number matches the one printed on the vial you receive. A real report for a different batch is still the wrong report.
| Size | Lot | Identity method | Purity | Test date |
|---|---|---|---|---|
| 2mg | Pending verification | Pending verification | Pending verification | Pending verification |
No lot documentation is published for PEG-MGF yet. Rather than display a placeholder certificate, this record shows the gap until each field has been verified against the lot in hand. The certificate index lists every lot the moment its report clears.
Solution arithmetic for the bench, with no administration guidance: the vial concentration calculator, preset to PEG-MGF.
Where the FDA stands on PEG-MGF
The FDA has not approved this compound for anything, and nothing in this catalogue is a medicine. Where a compound stands legally depends on what it is, what form it is in, what it is being used for and which country you are in, and it changes over time, so the status shown here carries the date it was last checked.
Status verified 2026-08-25. Regulatory positions move; check the primary source before relying on any summary, including this one.
It is sold here as laboratory material under the research-use restriction that closes this page, which is not an approval, and not a statement that the compound is safe, effective or right for any purpose.
PEG-MGF research: what the published studies examine
Status: No FDA-approved application. This compound is sold as laboratory material. Where research on it has been published, it sits at the animal, cell or early-human stage, and this record does not summarise what it found. A supplier is not a neutral judge of evidence about its own catalogue.
The starting point is real biology: IGF-1 exists in multiple isoforms, and one of them, IGF-IEc, is particularly responsive to mechanical signals and muscle damage, which is why it was named mechano growth factor. It differs from the systemic liver-type isoform IGF-IEa in its C-terminal E domain. The compound sold here is a synthetic peptide corresponding to that E domain, pegylated. Two gaps sit between the biology and the product.
The E-domain peptide is proposed to act through a mechanism distinct from IGF-1 receptor binding, and no receptor for it has been identified — so its mechanism is described by what it is not. And pegylation is a substantial modification: attaching polyethylene glycol changes size, clearance and tissue access, and a pegylated peptide is not pharmacokinetically the same molecule as the unmodified one, however similar the sequence.
| Reported observation | Model | Source |
|---|---|---|
| IGF-1 exists in multiple isoforms, and IGF-IEc — mechano growth factor — is described as particularly sensitive to mechanical signals and muscle damage, distinct from the systemic IGF-IEa isoform. Local IGF-1 produced within muscle for autocrine and paracrine action is implicated in repair and adaptation, acting in part through activation, proliferation and differentiation of satellite cells. | review of local growth factor biology in muscle and ageing | Harridge, Ageing and local growth factors in muscle, Scandinavian Journal of Medicine and Science in Sports (2003) |
| In C2C12 mouse muscle cells, growth hormone increased MGF mRNA at 1 hour while IGF-IEa mRNA rose only at 4 hours, and the same divergent pattern appeared with chemically induced muscle injury. Growth hormone also increased MyoD and M-cadherin expression with peaks parallel to MGF, which the authors interpret as consistent with satellite cell activation. | C2C12 mouse muscle cell line | Imanaka and colleagues, Growth hormone stimulates mechano growth factor expression and activates myoblast transformation in C2C12 cells, Kobe Journal of Medical Sciences (2008)This measures endogenous MGF expression in a cell line. It is not a study of administered MGF peptide, and certainly not of the pegylated form. |
Open questions. The distance between the cited literature and the product is larger here than on most pages in this catalogue, and it should be stated rather than glossed. The published work concerns an endogenous splice variant expressed by muscle in response to load and injury. The product is a synthetic fragment of that variant, chemically modified with polyethylene glycol. No receptor for the E-domain peptide has been identified, so there is no receptor-level mechanism to describe.
There are no human trials, no approved product, and the pegylated form specifically has almost no independent published literature — claims about it are largely extrapolation from work on endogenous MGF expression. Pegylation itself deserves attention when comparing lots: PEG attachment produces a heterogeneous product by nature, and identity and purity testing on a pegylated peptide is a materially harder analytical problem than on an unmodified one.
Each row above describes an observation in the stated model. None of it describes what PEG-MGF would do in a person or an animal outside that model, and none of it is a recommendation to use it for anything.
Questions about PEG-MGF
Where to buy PEG-MGF Peptide, and can I get it online?
How much does PEG-MGF Peptide cost?
What is the cheapest way to buy PEG-MGF Peptide?
What is PEG-MGF used for?
How does PEG-MGF work, and what does it do?
What does PEG-MGF do?
What is PEG-MGF peptide?
How do I verify the certificate of analysis is real?
FOR LABORATORY AND IN-VITRO RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR PERSONAL, MEDICAL, DIAGNOSTIC, THERAPEUTIC, OR RECREATIONAL USE.
