This page compares what is documented about Epithalon and GHK-Cu, rather than ranking them by effect. What each molecule is, the sizes and prices actually carried, what the certificate covers, and how the two differ on the bench. Everything here is research-use-only material and we do not publish outcome, dosing or administration content for any compound in the catalogue.
What is Epithalon and what is GHK-Cu?
Epithalon. Epithalon (AEDG) is the synthetic version of Khavinson's pineal tetrapeptide, studied in telomerase-activity and cellular-senescence models since the 1990s.
GHK-Cu. GHK-Cu has one of the longest citation trails in peptide science — from Pickart's 1973 isolation through modern work on collagen expression in cellular models.
How do Epithalon and GHK-Cu compare on price and size?
| Epithalon | GHK-Cu | |
|---|---|---|
| Sizes carried | 10 mg, 50 mg | 50 mg, 100 mg |
| From | $40.00 | $39.00 |
| Best price per unit | $2.18 / mg | $0.59 / mg |
| Availability | Backordered — waitlist | Backordered — waitlist |
| Certificate | Lot certificate on the product page | Lot certificate on the product page |
| Molecular formula | C14H22N4O9 | C14H24N6O4 |
| Molar mass | 390.35 g/mol | 340.38 g/mol |
| Source | PubChem CID 219042 | PubChem CID 73587 |
| Research area | telomere-biology research | copper-peptide research |
At their best sizes GHK-Cu works out at $0.59 per mg against $2.18 for Epithalon — 3.7 times more for the mg. Vial prices start at $40.00 and $39.00 respectively, which is the number most people compare and the one that says least, because the two are not sold in the same sizes. Full sizes, tier pricing and the lot certificate sit on the Epithalon page and the GHK-Cu page.
What is each one studied for?
What the published literature investigates, which is a different question from what either will do, and the only one of the two a supplier can answer.
Epithalon is studied in telomere-biology research. Telomere-biology research keeps the Khavinson peptides in circulation, with epithalon much the most-cited.
GHK-Cu is studied in copper-peptide research. Copper-peptide research remains active, with GHK-Cu's effect on gene expression in cellular models a recurring theme in the dermatological literature.
Studied in the same area does not make two compounds interchangeable, and the research library holds the per-compound documentation.
GHK-Cu vs Epithalon: how they differ on the bench
GHK-Cu. The blue is the copper complex itself: a GHK-Cu vial that is not blue is a red flag, and our identity testing covers both the peptide and the copper.
Epithalon. AEDG's aspartate is prone to isomerisation in storage — the exact failure mode our epithalon stability guide walks through.
What actually differs between GHK-Cu and Epithalon
Worth doing the arithmetic before comparing sizes: Epithalon is 390.35 g/mol and GHK-Cu is 340.38 g/mol, a factor of 1.1. A milligram of GHK-Cu therefore contains roughly 1.1 times as many molecules as a milligram of Epithalon, so two vials of the same labelled mass hold quite different amounts of substance. Equal milligrams are not equal moles, which is what the molarity calculator exists to convert, and it is the reason a price-per-milligram comparison and a price-per-mole comparison can point at different vials.
Identity is the other analytical axis, and it is settled per lot rather than per compound. Epithalon. Catalogued as Epitalon, and the certificate's identity test resolves to that. GHK-Cu. GHK-Cu as supplied is the copper(II) complex of that tripeptide, not the free peptide, so an identity test on this material does not resolve to the figures above.
Both are released against a certificate reporting identity, purity by the stated method and net peptide content, readable before anything is bought.
Which is better, GHK-Cu or Epithalon?
Neither GHK-Cu nor Epithalon is ranked against the other here, and the refusal is deliberate. Better, safer and stronger are questions about effects in a living system, and we sell neither compound for use in one — why none of these pages ranks two compounds sets out the reasoning in full.
What it does instead, for these two:
- GHK-Cu is the cheaper of the two per mg, at $0.59 against $2.18.
- Epithalon is the heavier molecule by a factor of 1.1, so equal milligrams are not equal moles.
- Both are carried in 2 sizes, and each lot carries its own certificate.
Every one of those is checkable before you buy.
Common questions
What is the difference between GHK-Cu and Epithalon?
Different molecules before anything else: GHK-Cu is C14H24N6O4 and Epithalon is C14H22N4O9. GHK-Cu has one of the longest citation trails in peptide science — from Pickart's 1973 isolation through modern work on collagen expression in cellular models. Epithalon (AEDG) is the synthetic version of Khavinson's pineal tetrapeptide, studied in telomerase-activity and cellular-senescence models since the 1990s.
Which one should I choose?
Epithalon is carried in 10 mg, 50 mg and GHK-Cu in 50 mg, 100 mg, each lot with its own certificate. Which of those suits the work is yours to decide; everything here is research-use-only rather than guidance for use in a human or an animal.
Do both Epithalon and GHK-Cu come with a certificate of analysis?
Neither is in stock at the moment, so in each case the certificate is the one attached to the lot that arrives. A certificate belongs to a lot, not to a product. It is linked from the product page, and reports identity, purity by the stated method, and net peptide content for the material actually in that lot.
Which is cheaper, GHK-Cu or Epithalon?
Per mg, GHK-Cu at $0.59 against $2.18, taking each one's best size. By vial they start at $40.00 for Epithalon and $39.00 for GHK-Cu, which is the comparison most people make and the one that says least, because the two are not sold in the same sizes.
Is a milligram of Epithalon the same as a milligram of GHK-Cu?
By mass yes, by amount of substance no. Epithalon is 390.35 g/mol and GHK-Cu is 340.38 g/mol, a factor of 1.1, so a milligram of GHK-Cu holds roughly 1.1 times as many molecules. Two vials with the same number on the label are not the same amount of substance, which is what the molarity calculator converts.
FOR LABORATORY AND IN-VITRO RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR PERSONAL, MEDICAL, DIAGNOSTIC, THERAPEUTIC, OR RECREATIONAL USE.